Therapeutic Functions of Artemisia Judaica in Rats Injected with Carbon Tetrachloride (Ccl4)

Abstract

There are many types of liver disease, which can be caused by infections, inherited conditions, obesity and misuse of alcohol. Over time, liver disease may lead to scarring and more serious complications , so we worked on this investigation to magnify the therapeutic applications of Artemisia judaica in carbon tetrachloride-injected rats (Ccl4). The experiment was carried out in a caged animal. All rats were fed a basal diet for one week before the study, and they were divided into five groups, each with six rats. As control negative normal rats (C–ve), the first group sample was fed only the basal diet for 28 days. The remaining rats (n=24) were injected with carbon tetrachloride (Ccl4). Four groups were fed varying concentrations of (5%, 10%, 15% Artemisia judaica, whereas one group was diagnosed with the illness and disease, and didn't even feed the experimental diet. The results showed that highest value of feed efficiency ratio (FER) was found in 15% Artemisia judaica. It is noticed that a significant decreases in BWG% for the control group compared to all groups. Also, The strongest effect in serum AST levels was recorded for group 5 which fed on 15% Artemisia Judaica, while the rats fed on different levels of Artemisia judaica were lower than the positive control group and higher than the negative control groups. The study recommended feeding Artemisia judaica  in different concentrations, especially 15%.