Development and the Study of the New Plant-Based Enterosorbent Tablets

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Tatiana Borisovna Trofimova, Andrey Anatolevich Kislitsyn, Valeriy Mikhailovich Poznyakovsky, Boisjoni Tokhiriyon, Nadezhda Nikolaevna Danko, Nina Grigorievna Chelnakova

Abstract

With the increasing number of patients suffering from IBS with constipation, medical specialists are giving more attention to plant-based dietary supplements. The health benefits associated with plant-based dietary supplements in nutrition prophylaxis and diet therapy are highly valued, as they assist in preventing and treating constipation and other IBS symptoms. A new plant-based enterosorbent tablets with microcrystalline cellulose; lactobacillus complex; Rosa canina fruits; anthelmintic complex with tansy and buckthorn bark; sublimated beets; polysorbovit; and senna were developed. Organoleptic and physico-chemical properties, microbiological indicators of quality and safety were studied during the production stage and after storing for 39 months. Twenty adult patients aged between 39 and 54 and diagnosed with IBS-C were selected for a 15-day-long clinical trial. The control group was made up of 15 patients with characteristics similar to the main group for age and sex match. Positive changes in the quality of life were confirmed by both the laboratory tests and the patient’s subjective assessment. The plant-based enterosorbent tablets assist in reducing the clinical manifestations of IBS-C and improve overall well-being.

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